Kavideza 600 mg. 50 mg. 300 mg Film-coated tablets

Indication

Treatment of HIV infection in adults and adolescents.

Dosage (summary)

One tablet once daily for adults and adolescents >40 kg.

Special Populations

• Elderly
• Renal impairment
• Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding; potential risk of neural tube defects.

Key Drug Interactions

• Metformin (contraindicated)
• Dofetilide (contraindicated)
• Pilsicainide (contraindicated)

Contraindications

• Hypersensitivity to abacavir, dolutegravir, lamivudine
• Moderate to severe hepatic impairment
• Creatinine clearance <50 mL/min

Common side effects

• Hypersensitivity reactions
• Nausea
• Insomnia
• Fatigue
• Rash

Counselling Points

• Screen for HLA-B*5701 allele before use.
• Do not restart after hypersensitivity reaction.
• Monitor for signs of lactic acidosis.