Amlodipine 5 & 10 Biotech. 5 or 10 mg Tablets
PDF Leaflet Revision Date: 28 July 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of angina pectoris and mild to moderate hypertension.
Dosage (summary)
Initial dose of 5 mg once daily, may increase to 10 mg after 10-14 days.
Onset of Action / Duration
Onset: 6-12 hours, Duration: 35-50 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excreted in breast milk.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Grapefruit juice
- Tacrolimus
- Simvastatin
Contraindications
- Hypersensitivity to dihydropyridines
Common side effects
- Dizziness
- Headache
- Palpitations
- Ankle swelling
- Fatigue
Counselling Points
- Monitor for dizziness or fatigue
- Avoid grapefruit juice
- Gradual withdrawal recommended
Serious warnings
- Caution in heart failure
- Risk of hypotension with overdose
On This Page
Loading package insert…
Medinsert AI
Hello! I am Medinsert Ai. What would you like to know about this professional information leaftleft?
