Everdexâ 1 Mg. 1 mg Film-coated Tablets
PDF Leaflet Revision Date: 22 January 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of early and advanced breast cancer in postmenopausal women.
Dosage (summary)
1 mg orally once daily for adults, no change for mild/moderate renal or hepatic impairment.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- Tamoxifen
- Oestrogen-containing therapies
Contraindications
- Hypersensitivity
- Pre-menopausal women
- Severe renal impairment
- Moderate/severe hepatic disease
Common side effects
- Headache
- Hot flushes
- Nausea
- Rash
- Arthralgia
- Asthenia
Counselling Points
- Monitor for signs of bone health issues.
- Report any unusual bleeding.
- Caution advised when driving if experiencing somnolence.
Serious warnings
- May reduce bone mineral density, increasing fracture risk.
- Not recommended for pre-menopausal women or children.
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