Eplipix 2,5 mg & 5 mg Film-coated tablets
PDF Leaflet Revision Date: 12 May 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of VTE and stroke in NVAF.
Dosage (summary)
2.5 mg or 5 mg orally twice daily depending on indication.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy; avoid breastfeeding.
Key Drug Interactions
- Strong CYP3A4 and P-gp inhibitors
- Antiplatelet agents
Contraindications
- Hypersensitivity to apixaban
- Active bleeding
- Severe renal disease
- Severe hepatic impairment
Common side effects
- Haemorrhage
- Contusion
- Epistaxis
- Gastrointestinal haemorrhage
Counselling Points
- Take with or without food
- Monitor for signs of bleeding
- Do not crush tablets unless necessary
Serious warnings
- Risk of bleeding
- Use with caution in patients with bleeding disorders
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