Burinex 1 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of oedema associated with heart failure, renal disease, and hepatic ascites.
Dosage (summary)
1 mg daily, may increase based on response; consider twice daily for refractory cases.
Onset of Action / Duration
Onset: 30 mins, Duration: 4-6 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Diabetic patients
Pregnancy & Breastfeeding
Avoid in first trimester; contraindicated in breastfeeding.
Key Drug Interactions
- Digitalis glycosides
- Antihypertensives
- NSAIDs
- Lithium
- Potassium depleting medicines
Contraindications
- Hypersensitivity to bumetanide
- Anuria
- Hepatic coma
- Electrolyte depletion
Common side effects
- Headache
- Dizziness
- Electrolyte disturbances
- Fatigue
- Abdominal pain
Counselling Points
- Monitor for dizziness
- Maintain potassium intake
- Report signs of SJS or TEN
Serious warnings
- Risk of SJS and TEN
- Electrolyte imbalance
- Caution in hypotension
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