Pecaset 150 mg & 500 mg Tablet
PDF Leaflet Revision Date: 22 April 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of metastatic breast, colorectal, and gastric cancer.
Dosage (summary)
1,250 mg/mu00b2 twice daily for 14 days, followed by 7 days rest; adjust for renal impairment.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to potential risks.
Key Drug Interactions
- Warfarin
- Sorivudine
- Phenytoin
- Leucovorin
Contraindications
- Hypersensitivity to capecitabine
- Severe renal impairment
- Severe hepatic impairment
- DPD deficiency
Common side effects
- Diarrhoea
- Nausea
- Neutropenia
- Fatigue
- Palmar-plantar erythrodysaesthesia
Counselling Points
- Take with water within 30 mins after meals.
- Report any signs of severe toxicity immediately.
- Use effective contraception during treatment.
Serious warnings
- Monitor for severe toxicity
- Risk of coagulopathy with anticoagulants
- Potential for cardiotoxicity
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