Decasone Injection 4 mg/ml INJECTION
PDF Leaflet Revision Date: 29 January 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Anti-inflammatory and immunosuppressive therapy, including COVID-19 treatment.
Dosage (summary)
0.5 to 20 mg daily; 6 mg IV once daily for COVID-19 up to 10 days.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Crosses placenta; may cause fetal adrenal suppression. Not recommended during breastfeeding.
Key Drug Interactions
- Liver enzyme inducers may reduce efficacy
- Potassium-depleting diuretics may cause hypokalaemia
Contraindications
- Hypersensitivity to dexamethasone
- Active tuberculosis
- Ocular herpes simplex
- Systemic infections
Common side effects
- Psychiatric disorders
- Hypertension
- Gastrointestinal ulceration
- Osteoporosis
Counselling Points
- Monitor for psychiatric symptoms
- Avoid live vaccines
- Carry steroid treatment card
Serious warnings
- Risk of anaphylaxis
- Adrenal suppression on withdrawal
- Increased infection risk
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