Innotere 20, Innotere 80, 20 mg/1 ml, 80 mg/4 ml Concentrate for solution for infusion

Innotere 20, Innotere 80, 20 mg/1 ml, 80 mg/4 ml Concentrate for solution for infusion

S4
PDF Leaflet Revision Date: 22 August 2025


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of various cancers including breast, lung, ovarian, prostate, and head and neck cancers.

Dosage (summary)

Administered as an IV infusion; typical doses range from 60 to 100 mg/mu00b2 every 3 weeks depending on cancer type.

Special Populations

  • Hepatic impairment
  • Elderly
  • Renal impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation due to teratogenic effects.

Key Drug Interactions

  • CYP3A4 inhibitors
  • Doxorubicin
  • Cisplatin

Contraindications

  • Hypersensitivity to docetaxel
  • Neutrophil count < 1500 cells/mmu00b3
  • Severe liver impairment

Common side effects

  • Neutropenia
  • Alopecia
  • Nausea
  • Vomiting
  • Stomatitis

Counselling Points

  • Monitor for hypersensitivity reactions
  • Use contraception during and after treatment
  • Avoid alcohol due to ethanol content

Serious warnings

  • Severe hypersensitivity reactions
  • Fluid retention
  • Increased risk of treatment-related mortality in liver impairment

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Innotere 20, Innotere 80, 20 mg/1 ml, 80 mg/4 ml Concentrate for solution for infusion
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