Doceturas 20, 80 & 160 Mg 20, 80 & 160 mg Concentrate for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including breast, lung, ovarian, and prostate cancer.
Dosage (summary)
75-100 mg/mu00b2 every 3 weeks; premedication with dexamethasone recommended.
Special Populations
- Hepatic impairment
- Elderly
- Paediatric population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; teratogenic effects observed.
Key Drug Interactions
- CYP3A4 inhibitors
- Dexamethasone
- Cisplatin
Contraindications
- Hypersensitivity to docetaxel
- Neutrophil count < 1500 cells/mmu00b3
- Severe liver impairment
Common side effects
- Neutropenia
- Alopecia
- Nausea
- Vomiting
- Fluid retention
Counselling Points
- Monitor for signs of hypersensitivity
- Avoid pregnancy during treatment
- Report any severe side effects immediately
Serious warnings
- Severe hypersensitivity reactions
- Fluid retention
- Potential for severe liver toxicity
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