Dulta 30 Mg. 60 Mg 30 mg. 60 mg DELAYED RELEASE CAPSULES
PDF Leaflet Revision Date: 09 October 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression and diabetic peripheral neuropathic pain.
Dosage (summary)
60 mg once daily; initial dose 30 mg for renal/hepatic impairment.
Onset of Action / Duration
Onset: 2-4 weeks, Duration: Not specified.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; may cause neonatal withdrawal symptoms.
Key Drug Interactions
- MAOIs
- CYP1A2 inhibitors
- CYP2D6 inhibitors
- Serotonergic medicines
Contraindications
- Hypersensitivity to duloxetine
- Children under 18
- Severe hepatic impairment
- Severe renal impairment
Common side effects
- Nausea
- Headache
- Dry mouth
- Somnolence
- Dizziness
Counselling Points
- Monitor for suicidal thoughts
- Avoid abrupt discontinuation
- Caution with alcohol and CNS depressants
Serious warnings
- Risk of suicidal thoughts
- Serotonin syndrome
- Hyponatraemia
- Increased blood pressure
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