Ferrimed D.S 100 mg Chewable Tablets

Iron (III)-hydroxide polymaltose complex in the Ferrimed u00ae range is indicated for the treatment of iron deficiency and iron deficiency anaemia.

Ferrimed u00ae D.S. Chewable Tablets: Therapeutic dose: Chew or swallow one to two tablets (100 mg to 200 mg elemental iron) per day. The tablets must be taken in divided doses with meals.

Cases of iron overload (haemochromatosis; haemosiderosis; chronic haemolysis or lead induced anaemia). Disturbances in iron utilisation (thalassaemia or sideroblastic anaemia). Patients showing hypersensitivity and intolerance to iron. Patients receiving repeated blood transfusions. All forms of anaemia without iron deficiency, e.g. megaloblastic anaemia stemming from Vitamin B 12 deficiency and pernicious anaemia. In cases of inflammatory conditions or malignancy, iron is deposited in the reticulo-endothelial system and iron mobilisation and utilisation do not occur until the underlying disease is treated.

Notice to diabetics: Ferrimed u00ae D.S. Chewable Tablets = 0,04 bread units per tablet.

The oral administration of iron preparations may cause gastro-intestinal irritation and abdominal pain with nausea and vomiting. Other gastro-intestinal effects may include either diarrhoea or constipation. The faeces may be coloured black. Lassitude and headache may occur.

Acute iron overdose can be divided into four stages. In the first phase of acute iron overdosage, which occurs up to 6 hours after oral ingestion, gastro-intestinal toxicity, notably vomiting and diarrhoea, predominates. Other effects may include cardiovascular disorders such as hypotension and tachycardia; metabolic changes including acidosis and hyperglycaemia; as well as central nervous system depression ranging from lethargy to coma. Patients with mild to moderate poisoning do not generally progress past this first phase. The second phase may occur at 6 to 24 hours after ingestion and is characterised by a temporary remission or clinical stabilisation. In the third phase gastro-intestinal toxicity recurs together with shock, metabolic acidosis, convulsions, coma, hepatic necrosis and jaundice, hypoglycaemia, coagulation disorders, oliguria or renal failure and pulmonary oedema. The fourth phase may occur several weeks after ingestion and is characterised by gastro-intestinal obstruction and possibly late hepatic damage. In treating acute iron poisoning, speed is essential to block absorption of iron from the alimentary tract. Emesis or lavage should be considered and serum-iron concentrations may be an aid to estimating the severity of the poisoning. Chelation therapy with desferrioxamine, according to the instructions on the package insert, may be necessary. Treatment is symptomatic and supportive.