Erlotinib Zydus 25/100/150 25 mg, 100 mg, 150 mg Tablets

Erlotinib Zydus 25/100/150 25 mg, 100 mg, 150 mg Tablets

S4
PDF Leaflet Revision Date: 23 August 2022


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of non-small cell lung cancer, bronchial adenocarcinoma, and pancreatic cancer.

Dosage (summary)

150 mg daily for NSCLC and bronchial adenocarcinoma; 100 mg daily with gemcitabine for pancreatic cancer.

Special Populations

  • Hepatic impairment
  • Renal impairment
  • Elderly population
  • Paediatric population

Pregnancy & Breastfeeding

Not recommended during pregnancy or breastfeeding.

Key Drug Interactions

  • CYP3A4 inducers/inhibitors
  • Warfarin
  • Statins

Contraindications

  • Severe hypersensitivity to erlotinib

Common side effects

  • Rash
  • Diarrhoea
  • Fatigue
  • Nausea

Counselling Points

  • Take on an empty stomach
  • Avoid smoking
  • Monitor for severe skin reactions

Serious warnings

  • Risk of ILD
  • Gastrointestinal perforation
  • Hepatic failure

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Erlotinib Zydus 25/100/150 25 mg, 100 mg, 150 mg Tablets
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