Aspepraz 40mg Injection
PDF Leaflet Revision Date: 15 November 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of Gastro-oesophageal Reflux Disease and prevention of rebleeding in ulcers.
Dosage (summary)
40 mg IV once daily for GORD; 80 mg bolus for bleeding ulcers.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Safety not established in pregnancy and lactation.
Key Drug Interactions
- Clopidogrel
- Warfarin
- Tacrolimus
Contraindications
- Hypersensitivity to esomeprazole
- Children
- Concomitant use with nelfinavir
- Concomitant use with atazanavir
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
Counselling Points
- Take the lowest effective dose for the shortest duration
- Monitor for signs of gastrointestinal infections
- Avoid driving if experiencing dizziness or blurred vision
Serious warnings
- Increased risk of gastrointestinal infections
- Risk of fracture
- Hypomagnesaemia
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