Nepexto 25 Ps, 50 Ps & 50 Prefilled Pen 25 mg, 50 mg Parenteral
PDF Leaflet Revision Date: 29 August 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis.
Dosage (summary)
Adults: 25 mg twice weekly or 50 mg weekly. Children: 0.4 mg/kg (max 25 mg) twice weekly or 0.8 mg/kg (max 50 mg) weekly.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Use only if clearly needed; crosses placenta and excreted in breast milk.
Key Drug Interactions
- Anakinra
- Abatacept
- Sulfasalazine
Contraindications
- Hypersensitivity to etanercept
- Active infections
- Sepsis
Common side effects
- Injection site reactions
- Infections
- Headache
- Allergic reactions
Counselling Points
- Monitor for infections
- Avoid live vaccines
- Report signs of TB or infections
- Consider contraception during treatment
Serious warnings
- Serious infections
- Tuberculosis risk
- Malignancies
- Hepatitis B reactivation
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