Ezesim 10/10, 10/20, 10/40, 10/80 Tablets
PDF Leaflet Revision Date: 07 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunctive therapy for primary hypercholesterolaemia and mixed hyperlipidaemia.
Dosage (summary)
Starting dose: 10/20 mg/day; range: 10/10 mg to 10/80 mg/day.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- CYP3A4 inhibitors
- Gemfibrozil
- Ciclosporin
- Danazol
- Amiodarone
- Verapamil
Contraindications
- Hypersensitivity
- Active liver disease
- Moderate to severe hepatic impairment
- Pregnancy
- Lactation
- Children
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Myopathy
- Rhabdomyolysis
Counselling Points
- Take in the evening with or without food.
- Report unexplained muscle pain or weakness.
- Avoid grapefruit juice.
Serious warnings
- Risk of myopathy/rhabdomyolysis
- Monitor liver enzymes
- Caution in alcohol use
Important Disclaimer
The Ezesim 10/10, 10/20, 10/40, 10/80 Tablets professional information leaflet below is the property of Forrester Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
