Grantryl 1 mg/1 ml & 3 mg/3 ml Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative.
Dosage (summary)
Adults: 1-3 mg IV prior to chemotherapy/radiotherapy; max 9 mg/24h. PONV: 1 mg IV prior to anesthesia.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated during pregnancy and lactation.
Key Drug Interactions
- Phenobarbital may increase clearance
- Co-administer with benzodiazepines and neuroleptics
Contraindications
- Hypersensitivity
- Children under 2 years
- Congenital long QT syndrome
Common side effects
- Headache
- Dizziness
- Somnolence
- Abdominal pain
- Constipation
Counselling Points
- Avoid driving if somnolence occurs
- Report any signs of myocardial ischemia
Serious warnings
- May cause dysrhythmias
- Monitor for myocardial ischemia
- Max 9 mg/24h
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