Amdocin 25 mg Capsules

Indication

Management of pain and inflammation associated with conditions such as arthritis, bursitis, and tendinitis.

Dosage (summary)

The usual adult dosage is 25 mg to 50 mg taken two to three times daily, depending on the severity of the condition.

Onset of Action / Duration

Onset of action is typically within 1 to 2 hours, with peak effects occurring within 2 to 4 hours.

Special Populations

• Elderly patients may require dose adjustments due to increased sensitivity.
• Patients with renal impairment should use with caution and may require dose adjustments.
• Patients with hepatic impairment should use with caution.

Pregnancy & Breastfeeding

Indomethacin is contraindicated during the third trimester of pregnancy. Use during lactation should be approached with caution, as it is excreted in breast milk.

Key Drug Interactions

• Increased risk of gastrointestinal bleeding when used with other NSAIDs or anticoagulants.
• May reduce the effectiveness of antihypertensive medications.
• Caution is advised when used with diuretics due to potential renal impairment.

Contraindications

• History of hypersensitivity to indomethacin or other NSAIDs.
• Active gastrointestinal bleeding or peptic ulcer disease.
• Severe renal or hepatic impairment.
• Pregnancy (third trimester).

Common side effects

• Gastrointestinal discomfort, nausea, and vomiting.
• Headache and dizziness.
• Increased blood pressure.
• Rash or other allergic reactions.

Counselling Points

• Take with food or milk to minimize gastrointestinal irritation.
• Avoid alcohol to reduce the risk of gastrointestinal side effects.
• Report any signs of gastrointestinal bleeding, such as black stools or vomiting blood.
• Inform healthcare provider of any other medications being taken.