Pomarza 1, 2, 3 & 4 1,0 mg, 2,0 mg, 3,0 mg & 4,0 mg Gelatin Capsules
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of adult patients with multiple myeloma after prior therapies.
Dosage (summary)
4 mg orally once daily on days 1-14 for PBd regimen; 4 mg/day on days 1-21 for Pd regimen.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; teratogenic effects expected.
Key Drug Interactions
- CYP1A2 inhibitors
- CYP3A4 inducers
- Dexamethasone
Contraindications
- Hypersensitivity to pomalidomide
- Pregnancy
- Lactation
- Females of childbearing potential not meeting criteria
Common side effects
- Neutropenia
- Thrombocytopenia
- Fatigue
- Dizziness
- Rash
Counselling Points
- Use effective contraception
- Report signs of infection
- Avoid driving if affected by dizziness
Serious warnings
- Severe birth defects
- Venous thromboembolism
- Progressive multifocal leukoencephalopathy
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