Adco-Prednisolone Syrup
Clinical Summary
Quick overview from the medicine insert
Indication
Management of inflammatory and autoimmune conditions such as asthma, rheumatoid arthritis, and allergic reactions.
Dosage (summary)
The usual dose for adults is 5 to 60 mg per day, depending on the condition being treated. For children, the dose is typically 0.1 to 2 mg/kg/day.
Onset of Action / Duration
Effects may be observed within 1 to 2 hours after oral administration, with peak effects occurring within 4 to 8 hours.
Special Populations
- Elderly patients may require dose adjustments.
- Patients with hepatic impairment may require dose adjustments.
- Patients with renal impairment may require dose adjustments.
Pregnancy & Breastfeeding
Prednisolone is classified as Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation as it may be excreted in breast milk.
Key Drug Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal side effects.
- Anticoagulants may have altered effects when used with prednisolone.
- Live vaccines may be less effective and should be avoided during treatment.
Contraindications
- Systemic fungal infections.
- Hypersensitivity to prednisolone or any component of the formulation.
- Active tuberculosis.
Common side effects
- Increased appetite.
- Weight gain.
- Mood changes.
- Insomnia.
- Gastrointestinal disturbances.
Counselling Points
- Take the medication as prescribed and do not discontinue abruptly without consulting a healthcare provider.
- Monitor for signs of infection, as prednisolone can suppress the immune system.
- Report any unusual mood changes or side effects to a healthcare provider.
Serious warnings
- Use with caution in patients with a history of peptic ulcer disease.
- Long-term use may lead to adrenal suppression.
- Monitor blood glucose levels in diabetic patients.
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