Remifentanil 5 Aspen 5 mg Injection
PDF Leaflet Revision Date: 03 October 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Narcotic analgesic for induction and maintenance of anaesthesia.
Dosage (summary)
Adults: 0.5-1.0 u03bcg/kg/min continuous infusion; initial bolus 1 u03bcg/kg over 30 seconds.
Onset of Action / Duration
Onset: 1-2 mins, Duration: 5-10 mins
Special Populations
- Elderly: reduce initial dose by 50%
- Renal impairment: no dosage adjustment needed
- Hepatic impairment: monitor closely
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established; crosses placenta and appears in breast milk.
Key Drug Interactions
- Increased risk of respiratory depression with benzodiazepines
- Decreased requirement for inhaled and IV anaesthetics
Contraindications
- Hypersensitivity to excipients
- Not for use without planned artificial ventilation
- Not recommended for epidural or intrathecal use
Common side effects
- Respiratory depression
- Bradycardia
- Hypotension
- Skeletal muscle rigidity
Counselling Points
- Monitor for signs of respiratory depression
- Avoid driving or operating machinery post-treatment
- Ensure alternative analgesia is in place before discontinuation
Serious warnings
- Risk of sedation and respiratory depression with concomitant sedatives
- Potential for withdrawal syndrome after prolonged use
Important Disclaimer
The Remifentanil 5 Aspen 5 mg Injection professional information leaflet below is the property of Aspen Sa Operations and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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