Remifentanil 1 Mg B. Braun, Remifentanil 2 Mg B. Braun, Remifentanil 5 Mg B. Braun, 1mg,2 mg, 5mg Sterile powder for solution for injection or infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Narcotic analgesic for induction and maintenance of anaesthesia.
Dosage (summary)
Adults: 0.5-1.0 u03bcg/kg/min continuous infusion; titrate based on response.
Onset of Action / Duration
Onset: 1-2 mins, Duration: 5-10 mins
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Obese patients
Pregnancy & Breastfeeding
Not established for safety in pregnancy; avoid breastfeeding for 24 hours post-administration.
Key Drug Interactions
- CNS depressants
- Other opioids
- Cardiac depressants
- Serotonergic agents
Contraindications
- Hypersensitivity to remifentanil
- Epidural or intrathecal use
- Use with nitrous oxide and oxygen alone at altitude
- Planned artificial ventilation required
Common side effects
- Respiratory depression
- Bradycardia
- Hypotension
- Muscle rigidity
Counselling Points
- Monitor for respiratory depression
- Avoid driving or operating machinery post-treatment
- Ensure alternative analgesia is planned before discontinuation
Serious warnings
- Respiratory and cardiovascular monitoring required
- Risk of tolerance and hyperalgesia
- Withdrawal symptoms may occur
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