Duosol 04. 555 mL Solution for haemofiltration
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of acute renal failure in ICU patients via continuous haemofiltration.
Dosage (summary)
Adults: 600-1200 mL/h; max 75 L/day. Pediatric: 150-1500 mL/h based on GFR.
Pregnancy & Breastfeeding
Considered safe during pregnancy and lactation; no expected risks.
Key Drug Interactions
- Electrolyte substitutions may alter serum composition.
- Digitalis toxicity may be masked or precipitated.
- Vitamin D and calcium products may increase hypercalcaemia risk.
Contraindications
- Hyperkalaemia
- Metabolic alkalosis
- Severe hypercatabolic state
- Inadequate blood flow from vascular access
- Increased risk of hemorrhage
Common side effects
- Electrolyte disturbances
- Hyperglycaemia
- Nausea
- Vomiting
- Muscle cramps
Counselling Points
- Ensure proper hydration and electrolyte monitoring.
- Use aseptic technique during administration.
- Discard any unused solution after preparation.
Serious warnings
- Monitor fluid and electrolyte balance closely.
- Inspect solution for contamination before use.
- Risk of precipitation in tubing lines.
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