Eurostib 200 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of advanced renal cell carcinoma, hepatocellular carcinoma, and differentiated thyroid carcinoma.
Dosage (summary)
400 mg daily (2 x 200 mg tablets) taken twice daily.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; potential for teratogenic effects.
Key Drug Interactions
- Warfarin
- Docetaxel
- Neomycin
Contraindications
- Hypersensitivity to sorafenib
- Pregnancy
- Lactation
Common side effects
- Diarrhoea
- Fatigue
- Alopecia
- Rash
- Hand foot skin reaction
Counselling Points
- Avoid pregnancy during treatment
- Monitor blood pressure regularly
- Report any signs of bleeding
Serious warnings
- Hypertension
- Cardiac ischaemia
- Gastrointestinal perforation
- QT prolongation
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