Muscuron 4 mg/vial Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to general anaesthesia for intubation and muscle relaxation.
Dosage (summary)
Intubating dose: 0.08-0.10 mg/kg IV; Maintenance: 0.03-0.05 mg/kg.
Onset of Action / Duration
Onset: 90-120 secs, Duration: 24-60 mins.
Special Populations
- Hepatic impairment
- Renal failure
- Severe obesity
- Neuromuscular disease
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established.
Key Drug Interactions
- Anaesthetics (e.g., isoflurane, halothane)
- Aminoglycosides
- Corticosteroids
- Magnesium salts
Contraindications
- Hypersensitivity to vecuronium or excipients
- Children under 3 months
- Pregnancy and lactation
Common side effects
- Hypersensitivity reactions
- Flaccid paralysis
- Respiratory insufficiency
- Hypotension
Counselling Points
- Monitor respiratory function during recovery.
- Avoid use in patients with known hypersensitivity.
- Ventilatory support mandatory until recovery.
Serious warnings
- Respiratory paralysis possible
- Anaphylactic reactions may occur
- Residual neuromuscular blockade
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