Adco Contromet Tablet & Syrub
Clinical Summary
Quick overview from the medicine insert
Indication
Management of nausea and vomiting, including that associated with chemotherapy, radiotherapy, and postoperative states.
Dosage (summary)
Adults: 10 mg to 20 mg taken 30 minutes before meals and at bedtime. Maximum daily dose: 60 mg. Children: 0.1 mg/kg to 0.15 mg/kg up to a maximum of 10 mg, taken 30 minutes before meals.
Onset of Action / Duration
Onset of action: 30 to 60 minutes; Duration of action: 1 to 2 hours.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Metoclopramide is excreted in breast milk; caution is advised when administered to nursing mothers.
Key Drug Interactions
- CNS depressants may enhance sedative effects.
- Anticholinergic agents may reduce the effectiveness of Metoclopramide.
- Drugs that affect gastric emptying may interact with Metoclopramide.
Contraindications
- Hypersensitivity to Metoclopramide or any component of the formulation.
- Gastrointestinal obstruction, perforation, or hemorrhage.
- Pheochromocytoma.
- Seizure disorders.
Common side effects
- Drowsiness
- Fatigue
- Restlessness
- Dizziness
- Diarrhea
- Extrapyramidal symptoms
Counselling Points
- Avoid alcohol while taking this medication.
- Inform healthcare provider if experiencing any unusual movements or symptoms.
- Take the medication as prescribed and do not exceed the recommended dose.
- Report any signs of allergic reaction, such as rash or difficulty breathing.
Serious warnings
- Long-term use may lead to tardive dyskinesia.
- Use with caution in patients with a history of depression.
- Monitor for signs of neuroleptic malignant syndrome.
Important Disclaimer
The Adco Contromet Tablet & Syrub professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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