Adco Everolimus Tablets
PDF Leaflet Revision Date: 29 April 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Palliative treatment for advanced renal cell carcinoma, SEGA, advanced breast cancer, and renal angiomyolipoma.
Dosage (summary)
10 mg orally once daily; reduce to 5 mg if needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- CYP3A4 inducers
- Live vaccines
Contraindications
- Hypersensitivity to everolimus
- Concomitant use of live vaccines
Common side effects
- Stomatitis
- Pneumonitis
- Fatigue
- Hyperglycaemia
Counselling Points
- Monitor for respiratory symptoms
- Avoid live vaccines
- Use contraception during treatment
Serious warnings
- Non-infectious pneumonitis
- Increased risk of infections
- Renal failure events
Important Disclaimer
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