Adco Magnesium Sulphate 50% Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Used for the treatment of severe hypomagnesemia, eclampsia, and as a tocolytic agent in preterm labor.
Dosage (summary)
Administer 2 mL (1 g) intravenously or intramuscularly, may repeat as necessary based on clinical response.
Onset of Action / Duration
Onset of action is typically within 30 minutes; duration of effect varies based on indication.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with cardiac disease
Pregnancy & Breastfeeding
Use in pregnancy only if clearly needed; magnesium sulfate crosses the placenta. Caution advised during lactation.
Key Drug Interactions
- May enhance the effects of neuromuscular blocking agents.
- Caution with concomitant use of other CNS depressants.
Contraindications
- Severe renal impairment
- Heart block
- Myasthenia gravis
Common side effects
- Flushing
- Sweating
- Hypotension
- Respiratory depression
- Nausea
Counselling Points
- Inform patients about the potential for drowsiness and dizziness.
- Advise to report any signs of allergic reactions, such as rash or difficulty breathing.
- Encourage patients to stay hydrated.
Serious warnings
- Monitor serum magnesium levels during therapy.
- Caution in patients with pre-existing heart conditions.
- Risk of hypermagnesemia, especially in patients with renal impairment.
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