Adco Mefenamic Acid 50mg/ml Suspension

Indication

Management of mild to moderate pain, including dysmenorrhea and pain associated with inflammation.

Dosage (summary)

Children aged 2-7 years: 25 mg (2.5 ml) three times daily. Children aged 7-14 years: 50 mg (5 ml) three times daily. Adults: 500 mg initially, followed by 250 mg every 6 hours as needed.

Onset of Action / Duration

Onset of action is typically within 1 hour, with a duration of effect lasting up to 6 hours.

Special Populations

• Elderly patients may require dose adjustment due to increased risk of adverse effects.
• Patients with renal impairment should use with caution and may require dose adjustment.

Pregnancy & Breastfeeding

Mefenamic acid is contraindicated during the third trimester of pregnancy. Use during lactation should be avoided unless deemed essential by a healthcare provider.

Key Drug Interactions

• May enhance the effects of anticoagulants such as warfarin.
• Concurrent use with other NSAIDs may increase the risk of gastrointestinal adverse effects.
• May reduce the effectiveness of antihypertensive medications.

Contraindications

• Hypersensitivity to mefenamic acid or any component of the formulation.
• Active peptic ulcer disease or history of recurrent ulceration.
• Severe renal or hepatic impairment.

Common side effects

• Gastrointestinal disturbances (nausea, vomiting, diarrhea, constipation).
• Dizziness or headache.
• Rash or other allergic reactions.

Counselling Points

• Take with food or milk to minimize gastrointestinal irritation.
• Do not exceed the recommended dosage.
• Report any signs of gastrointestinal bleeding, such as black stools or vomiting blood.