Adco Meropenem 500mg & 1g Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Meropenem is indicated for the treatment of infections caused by susceptible strains of designated microorganisms in the following conditions: intra-abdominal infections, meningitis, pneumonia, skin and soft tissue infections, and urinary tract infections.
Dosage (summary)
The recommended dosage for adults is 500 mg to 1 g administered intravenously every 8 hours, depending on the severity of the infection and renal function.
Onset of Action / Duration
The onset of action is typically within 30 minutes to 1 hour after intravenous administration.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Meropenem should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether meropenem is excreted in human milk; caution should be exercised when administering to nursing mothers.
Key Drug Interactions
- Probenecid may increase the plasma concentration of meropenem.
- Concurrent use with other nephrotoxic drugs may increase the risk of renal toxicity.
Contraindications
- Hypersensitivity to meropenem or any component of the formulation.
- History of severe allergic reactions to beta-lactam antibiotics.
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Rash
- Seizures (in patients with CNS disorders)
- Elevated liver enzymes
Counselling Points
- Inform patients to report any signs of allergic reactions, such as rash, itching, or difficulty breathing.
- Advise patients to complete the full course of therapy even if they feel better.
- Instruct patients to maintain adequate hydration during treatment.
Serious warnings
- Caution in patients with a history of seizures.
- Monitor renal function during treatment, especially in patients with renal impairment.
- Risk of Clostridium difficile-associated diarrhea.
Important Disclaimer
The Adco Meropenem 500mg & 1g Injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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