Amaryl Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet and exercise for Type 2 diabetes mellitus.
Dosage (summary)
Initial: 1 mg once daily, max: 8 mg.
Onset of Action / Duration
Onset: 30 mins, Duration: 5-8 hours
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended during pregnancy or breastfeeding.
Key Drug Interactions
- CYP2C9 inducers/inhibitors
- Insulin
- MAO-inhibitors
- ACE-inhibitors
Contraindications
- Hypersensitivity to glimepiride
- Pregnancy
- Breastfeeding
- Impaired liver function
- Type 1 diabetes
Common side effects
- Hypoglycaemia
- Nausea
- Diarrhoea
- Rashes
Counselling Points
- Monitor blood glucose regularly
- Take before meals
- Carry glucose for hypoglycaemia
Serious warnings
- Increased risk of cardiovascular mortality
- Serious hypoglycaemia risk
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