Apize 5/10/15/30 Mg 5mg,10mg, 15mg, 30mg Tablet

Apize 5/10/15/30 Mg 5mg,10mg, 15mg, 30mg Tablet

S5
PDF Leaflet Revision Date: 21 February 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of schizophrenia and acute manic episodes in Bipolar I disorder.

Dosage (summary)

Starting dose: 10-15 mg/day; Maintenance: 15 mg/day; Max: 30 mg/day.

Special Populations

  • Elderly
  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Safety in pregnancy not established; excreted in breast milk.

Key Drug Interactions

  • CYP3A4 inhibitors
  • CYP2D6 inhibitors
  • CYP3A4 inducers

Contraindications

  • Hypersensitivity to aripiprazole
  • Children under 18

Common side effects

  • Akathisia
  • Nausea
  • Sedation
  • Dizziness

Counselling Points

  • Monitor for suicidal thoughts
  • Avoid alcohol
  • Caution with driving

Serious warnings

  • Risk of suicide
  • Neuroleptic Malignant Syndrome
  • Tardive dyskinesia

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Apize 5/10/15/30 Mg 5mg,10mg, 15mg, 30mg Tablet
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