Aranesp Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of symptomatic anaemia in chronic renal failure and cancer patients receiving chemotherapy.
Dosage (summary)
Initial dose: 0.45 u03bcg/kg once weekly or 0.75 u03bcg/kg every two weeks; adjust based on haemoglobin response.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Caution in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Ciclosporin
- Tacrolimus
Contraindications
- Hypersensitivity
- Poorly controlled hypertension
Common side effects
- Hypertension
- Stroke
- Thromboembolic events
- Convulsions
- Allergic reactions
Counselling Points
- Monitor for signs of allergic reactions
- Rotate injection sites
- Report any unusual symptoms immediately
Serious warnings
- Increased risk of death and serious cardiovascular events
- Monitor blood pressure
- Avoid haemoglobin > 12 g/dl
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