Arbin Co 150/12,5mg or 300/12,5mg FC tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hypertension and heart failure.
Dosage (summary)
The usual starting dose is 150 mg of Irbesartan and 12.5 mg of Hydrochlorothiazide once daily. The dose may be adjusted based on blood pressure response.
Onset of Action / Duration
Antihypertensive effect typically observed within 1-2 hours, with peak effect at 4-6 hours. Full effect may take several weeks.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy and lactation due to potential harm to the fetus and infant.
Key Drug Interactions
- Other antihypertensive agents may enhance the hypotensive effect.
- Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect.
- Potassium-sparing diuretics may increase the risk of hyperkalemia.
Contraindications
- Hypersensitivity to Irbesartan, Hydrochlorothiazide, or any component of the formulation.
- Severe renal impairment.
- Anuria.
Common side effects
- Dizziness
- Fatigue
- Hypotension
- Electrolyte imbalances (e.g., hypokalemia)
- Renal impairment
Counselling Points
- Advise patients to take the medication at the same time each day.
- Encourage patients to maintain adequate hydration.
- Inform patients about the potential for dizziness, especially after the first dose.
- Advise regular monitoring of blood pressure and electrolytes.
Serious warnings
- Use with caution in patients with a history of renal disease.
- Monitor for signs of hypotension, especially in volume-depleted patients.
- Discontinue use if angioedema occurs.
Important Disclaimer
The Arbin Co 150/12,5mg or 300/12,5mg FC tablets professional information leaflet below is the property of Austell Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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