Atorvastatin Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunct to diet for hypercholesterolaemia and cardiovascular risk reduction.
Dosage (summary)
Starting dose: 10 mg once daily; max 80 mg depending on indication.
Onset of Action / Duration
Onset: 2 weeks, Duration: up to 30 hours.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- Gemfibrozil
- Fusidic acid
- Colchicine
Contraindications
- Hypersensitivity
- Active liver disease
- Pregnancy
- Lactation
Common side effects
- Myalgia
- Headache
- Constipation
- Nausea
Counselling Points
- Report unexplained muscle pain
- Avoid grapefruit juice
- Use effective contraception
Serious warnings
- Risk of rhabdomyolysis
- Liver function abnormalities
- Haemorrhagic stroke risk
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