Avonex 30 micrograms/0,5 ml Solution for injection

Indication

Treatment of relapsing forms of multiple sclerosis (MS).

Dosage (summary)

30 micrograms (0.5 ml) administered by subcutaneous injection once a week.

Onset of Action / Duration

Initial effects may be observed within a few weeks, with maximum benefit typically seen after several months of treatment.

Special Populations

• Elderly patients
• Patients with hepatic impairment
• Patients with renal impairment
• Patients with a history of depression

Pregnancy & Breastfeeding

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised when administering to nursing mothers.

Key Drug Interactions

• Other immunomodulatory therapies
• Medications that affect liver enzymes
• Antidepressants

Contraindications

• Hypersensitivity to interferon beta-1A or any excipients
• Severe depression or suicidal ideation
• Severe liver disease

Common side effects

• Flu-like symptoms (fever, chills, fatigue)
• Injection site reactions (redness, swelling, pain)
• Headache
• Nausea
• Depression

Counselling Points

• Instruct patients on proper injection technique.
• Advise patients to report any signs of depression or suicidal thoughts.
• Encourage adherence to the prescribed dosing schedule.
• Inform patients about potential flu-like symptoms and how to manage them.