Baximo 25 mg/100 mg Powder for concentrate for solution for infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
First-line treatment for specific leukemias and lymphomas.
Dosage (summary)
100 mg/mu00b2 on days 1 and 2 every 4 weeks for CLL; 90 mg/mu00b2 with rituximab for NHL.
Onset of Action / Duration
Onset: 30 mins, Duration: 4 weeks
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- CYP1A2 inhibitors
- Myelosuppressive agents
- Ciclosporin
- Tacrolimus
Contraindications
- Hypersensitivity
- Severe hepatic impairment
- Severe bone marrow suppression
- Pregnancy
- Lactation
Common side effects
- Infection
- Leukopenia
- Nausea
- Vomiting
- Fatigue
Counselling Points
- Monitor for signs of infection
- Use effective contraception
- Avoid driving if experiencing ataxia or somnolence
Serious warnings
- Myelosuppression
- Infection risk
- Hepatitis B reactivation
- Severe skin reactions
- Cardiac disorders
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