Carbosin 50mg / 5ml. 150mg / 15ml. 450 mg / 45ml. 600mg / 60ml Injection

Carbosin 50mg / 5ml. 150mg / 15ml. 450 mg / 45ml. 600mg / 60ml Injection

S4
PDF Leaflet Revision Date: 7 July 2006

API: Carboplatin | Company: Teva

Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of advanced ovarian carcinoma and limited evidence for small cell lung carcinoma.

Dosage (summary)

400 mg/m2 IV as a single dose; adjust for renal impairment and elderly.

Special Populations

  • Elderly
  • Renal impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy; safety in lactation not established.

Key Drug Interactions

  • Nephrotoxic compounds
  • Aminoglycosides

Contraindications

  • Severe hypersensitivity to carboplatin
  • Severe renal impairment (creatinine clearance u2264 20 ml/min)
  • Severe myelosuppression

Common side effects

  • Nausea
  • Vomiting
  • Myelosuppression
  • Hypersensitivity reactions

Counselling Points

  • Avoid pregnancy during treatment
  • Use effective contraception
  • Report any signs of allergic reactions

Serious warnings

  • Risk of anaphylaxis
  • Myelosuppression
  • Monitor renal and hepatic function

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Carbosin 50mg / 5ml. 150mg / 15ml. 450 mg / 45ml. 600mg / 60ml Injection
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