Carbosin 50mg / 5ml. 150mg / 15ml. 450 mg / 45ml. 600mg / 60ml Injection
PDF Leaflet Revision Date: 7 July 2006
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of advanced ovarian carcinoma and limited evidence for small cell lung carcinoma.
Dosage (summary)
400 mg/m2 IV as a single dose; adjust for renal impairment and elderly.
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; safety in lactation not established.
Key Drug Interactions
- Nephrotoxic compounds
- Aminoglycosides
Contraindications
- Severe hypersensitivity to carboplatin
- Severe renal impairment (creatinine clearance u2264 20 ml/min)
- Severe myelosuppression
Common side effects
- Nausea
- Vomiting
- Myelosuppression
- Hypersensitivity reactions
Counselling Points
- Avoid pregnancy during treatment
- Use effective contraception
- Report any signs of allergic reactions
Serious warnings
- Risk of anaphylaxis
- Myelosuppression
- Monitor renal and hepatic function
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