Casfolred 50, Casfolred 70 50 mg, 70 mg Lyophilised powder for concentrate for solution for infusion
PDF Leaflet Revision Date: 12 March 2020
Clinical Summary
Quick overview from the medicine insert
Indication
Empirical therapy for presumed fungal infections and treatment of invasive candidiasis and aspergillosis.
Dosage (summary)
Adults: 70 mg loading dose on Day 1, then 50 mg daily. Adjust for hepatic impairment.
Special Populations
- Paediatric patients
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Not recommended in pregnancy; unknown if excreted in breast milk.
Key Drug Interactions
- Ciclosporin increases AUC by 35%
- Tacrolimus levels decreased by 26%
Contraindications
- Hypersensitivity to caspofungin
- Severe hepatic insufficiency
Common side effects
- Nausea
- Vomiting
- Rash
- Headache
- Elevated liver enzymes
Counselling Points
- Administer by slow IV infusion
- Monitor for allergic reactions
- Avoid use with certain hepatic inducers
Serious warnings
- Anaphylaxis risk
- Monitor liver function
- Potential for Stevens-Johnson Syndrome
Important Disclaimer
The Casfolred 50, Casfolred 70 50 mg, 70 mg Lyophilised powder for concentrate for solution for infusion professional information leaflet below is the property of Dr Reddy’S Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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