Comarestol 50 µg/ 5 mg/ml Ophthalmic Solution
Clinical Summary
Quick overview from the medicine insert
Indication
Reduction of intraocular pressure in open angle glaucoma and ocular hypertension.
Dosage (summary)
One drop in the affected eye(s) once daily.
Onset of Action / Duration
Onset: 1 hour, Duration: up to 24 hours
Special Populations
- Elderly
- Patients with cardiovascular diseases
- Patients with respiratory disorders
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Concomitant use with other beta-blockers
- Hypoglycaemic medicines
- Phenothiazines
Contraindications
- Hypersensitivity to components
- Reactive airway disease
- Cardiac failure
Common side effects
- Eye irritation
- Increased iris pigmentation
- Headache
Counselling Points
- Inform about potential eye color change
- Avoid contact lenses during application
- Monitor for respiratory symptoms
Serious warnings
- Systemic absorption may occur
- Caution in patients with asthma
- Potential for severe bradycardia
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