Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution

Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution

S3
PDF Leaflet Revision Date: 17 February 2025

API: Brimonidine Tartrate | Company: AbbVie

Clinical Summary

Quick overview from the medicine insert

Indication

Control of intraocular pressure in chronic open-angle glaucoma or ocular hypertension.

Dosage (summary)

One drop in affected eye(s) twice daily, 12 hours apart.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Not recommended during pregnancy or breastfeeding.

Key Drug Interactions

  • MAO inhibitors
  • CNS depressants
  • Beta-blockers

Contraindications

  • Hypersensitivity
  • Reactive airway disease
  • Severe cardiac conditions
  • Patients under 18 years

Common side effects

  • Conjunctival hyperaemia
  • Burning sensation
  • Bradycardia
  • Somnolence

Counselling Points

  • Avoid contact with the eye tip
  • Remove contact lenses before use
  • Monitor for allergic reactions

Serious warnings

  • Respiratory and cardiac reactions
  • Caution in patients with asthma
  • Potential for systemic absorption
Important Disclaimer

The Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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