Convulex Range 50mg / 1ml, 150mg. 300mg. 500mg Syrup, Capsules
PDF Leaflet Revision Date: 26 January 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Epilepsy, acute mania in bipolar disorder, migraine prophylaxis.
Dosage (summary)
Adults: 600-2600 mg/day in divided doses; Children: 15-40 mg/kg/day.
Special Populations
- Children under 3 years
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; effective contraception required for women of childbearing potential.
Key Drug Interactions
- Increased sedation with phenobarbitone
- Decreased phenytoin levels
- Increased zidovudine toxicity
Contraindications
- Hypersensitivity to valproic acid
- Active liver disease
- Porphyria
- Mitochondrial disorders
Common side effects
- Thrombocytopenia
- Nausea
- Weight gain
- Increased liver enzymes
Counselling Points
- Monitor for signs of liver dysfunction
- Use effective contraception
- Do not discontinue abruptly
Serious warnings
- Risk of hepatic failure
- Pancreatitis
- Suicidal ideation
Important Disclaimer
The Convulex Range 50mg / 1ml, 150mg. 300mg. 500mg Syrup, Capsules professional information leaflet below is the property of Acino Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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