Cusyn 500 mg POWDER FOR SOLUTION FOR INFUSION
PDF Leaflet Revision Date: 23 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Indicated for complicated skin infections and Staphylococcus aureus bloodstream infections.
Dosage (summary)
cSSSI: 4 mg/kg IV daily; SAB/RIE: 6 mg/kg IV daily.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding not established.
Key Drug Interactions
- Increased risk of myopathy with statins
- False PT/INR prolongation with certain assays
Contraindications
- Hypersensitivity to daptomycin
- Treatment of pneumonia
Common side effects
- Dizziness
- Nausea
- Rash
- Increased CPK
- Infusion site reactions
Counselling Points
- Monitor for muscle pain and CPK levels
- Avoid driving if dizzy
- Report any allergic reactions immediately
Serious warnings
- Risk of myopathy
- Eosinophilic pneumonia
- Severe cutaneous adverse reactions
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