Doribax 500mg Injection
PDF Leaflet Revision Date: 28 December 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible bacteria.
Dosage (summary)
500 mg IV every 8 hours; adjust for renal impairment.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Safety not established in pregnancy or lactation.
Key Drug Interactions
- Probenecid
- Valproic acid
Contraindications
- Hypersensitivity to doripenem or beta-lactams
Common side effects
- Nausea
- Diarrhoea
- Headache
- Phlebitis
Counselling Points
- Monitor for allergic reactions
- Report severe diarrhea
- Avoid use in absence of infection
Serious warnings
- Increased mortality in ventilator-associated pneumonia
- Serious hypersensitivity reactions
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