Dotarem And Dotarem Prefilled Syringes 100 m Solution for injection in vials and prefilled syringes.
PDF Leaflet Revision Date: 03 November 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Enhancement of contrast in MRI for diagnostic purposes.
Dosage (summary)
Adults: 0.1 mmol/kg (0.2 ml/kg); max 0.2 mmol/kg (0.4 ml/kg) if needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Use in pregnancy only if essential; minimal excretion in breast milk.
Key Drug Interactions
- Beta-blockers
- Vasoactive substances
Contraindications
- Hypersensitivity to gadoteric acid or gadolinium
Common side effects
- Nausea
- Headache
- Injection site reactions
Counselling Points
- Monitor for allergic reactions
- Keep emergency equipment ready during administration
Serious warnings
- Risk of hypersensitivity reactions
- Nephrogenic systemic fibrosis in severe renal impairment
Important Disclaimer
The Dotarem And Dotarem Prefilled Syringes 100 m Solution for injection in vials and prefilled syringes. professional information leaflet below is the property of Guerbet South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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