Durogesic 12 _g/h. 25 _g/h. 50 _g/h. 75 _g/h. 100 _g/h Transdermal patch
PDF Leaflet Revision Date: 28 May 2018
Clinical Summary
Quick overview from the medicine insert
Indication
Management of chronic intractable pain requiring opioid analgesia.
Dosage (summary)
Opioid-tolerant adults: titrate based on previous opioid use. Replace patch every 72 hours.
Onset of Action / Duration
Onset: 12-24 hours, Duration: 72 hours
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; may cause respiratory depression in newborns.
Key Drug Interactions
- CYP3A4 inhibitors
- Other CNS depressants
- MAOIs
Contraindications
- Pregnancy
- Lactation
- Children < 2 years
- Hypersensitivity to fentanyl
Common side effects
- Somnolence
- Nausea
- Constipation
- Dizziness
Counselling Points
- Avoid heat exposure
- Do not cut patches
- Monitor for signs of misuse
Serious warnings
- Risk of respiratory depression
- Not for acute pain
- Monitor for opioid toxicity
Important Disclaimer
The Durogesic 12 _g/h. 25 _g/h. 50 _g/h. 75 _g/h. 100 _g/h Transdermal patch professional information leaflet below is the property of Janssen Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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