Dytorez 10/10 ,10/20, 10/40 & 10/80 10 mg, 20 mg, 40 mg, 80 mg Tablets
PDF Leaflet Revision Date: 24 January 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Adjunctive therapy for primary and homozygous familial hypercholesterolaemia.
Dosage (summary)
Starting dose: 10/10 mg once daily; max dose varies by indication.
Onset of Action / Duration
Onset: 2 weeks, Maximum response: 4 weeks
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- CYP3A4 inhibitors
- Bile acid sequestrants
- Warfarin
Contraindications
- Hypersensitivity to components
- Pregnancy
- Lactation
- Moderate to severe hepatic impairment
- Active liver disease
Common side effects
- Myopathy
- Rhabdomyolysis
- Increased transaminases
- Abdominal pain
- Fatigue
Counselling Points
- Monitor for muscle pain or weakness.
- Avoid alcohol.
- Use effective contraception in women of childbearing age.
Serious warnings
- Liver effects
- Risk of myopathy
- Haemorrhagic stroke risk in certain patients
Important Disclaimer
The Dytorez 10/10 ,10/20, 10/40 & 10/80 10 mg, 20 mg, 40 mg, 80 mg Tablets professional information leaflet below is the property of Pharma Dynamics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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