Entocord 0,02 Mg/Ml (Enema) 0,02 mg/ml Dispersible tablet and solution for rectal suspension

Indication

Ulcerative colitis involving the rectum and sigmoid colon.

Dosage (summary)

One enema nightly for 4 weeks; may extend to 8 weeks if no remission.

Onset of Action / Duration

Onset: 2-4 weeks, Duration: Not specified.

Special Populations

• Elderly
• Renal impairment
• Hepatic impairment

Pregnancy & Breastfeeding

Safety in pregnancy and breastfeeding not established; corticosteroids are teratogenic.

Key Drug Interactions

• CYP3A inhibitors (e.g., ketoconazole)
• CYP3A4 inducers (e.g., carbamazepine)

Contraindications

• Hypersensitivity to budesonide
• Bacterial, fungal, or viral infections
• Children

Common side effects

• Nausea
• Diarrhoea
• Depression
• Urticaria

Counselling Points

• Administer enema at bedtime
• Monitor for systemic side effects
• Report any allergic reactions