Everdexâ 1 Mg. 1 mg Film-coated Tablets

Everdexâ 1 Mg. 1 mg Film-coated Tablets

S4
PDF Leaflet Revision Date: 22 January 2022


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of early and advanced breast cancer in postmenopausal women.

Dosage (summary)

1 mg orally once daily for adults, no change for mild/moderate renal or hepatic impairment.

Special Populations

  • Renal impairment
  • Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation.

Key Drug Interactions

  • Tamoxifen
  • Oestrogen-containing therapies

Contraindications

  • Hypersensitivity
  • Pre-menopausal women
  • Severe renal impairment
  • Moderate/severe hepatic disease

Common side effects

  • Headache
  • Hot flushes
  • Nausea
  • Rash
  • Arthralgia
  • Asthenia

Counselling Points

  • Monitor for signs of bone health issues.
  • Report any unusual bleeding.
  • Caution advised when driving if experiencing somnolence.

Serious warnings

  • May reduce bone mineral density, increasing fracture risk.
  • Not recommended for pre-menopausal women or children.
Important Disclaimer

The Everdexâ 1 Mg. 1 mg Film-coated Tablets professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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