Evorel 1,6 mg/ 3,2 mg/ 4,8 mg/ 6,4 mg Transdermal patch.

Indication

Treatment of menopausal symptoms and prevention of post-menopausal osteoporosis.

Dosage (summary)

Apply twice weekly; initiate with EVOREL 50, adjust as needed.

Special Populations

• Elderly
• Liver impairment
• Kidney impairment

Pregnancy & Breastfeeding

Contraindicated in pregnancy and lactation.

Key Drug Interactions

• Barbiturates
• Carbamazepine
• Rifampicin
• St. John's wort
• Lamotrigine

Contraindications

• Hypersensitivity to estrogen
• Breast cancer
• Endometrial cancer
• Undiagnosed genital bleeding
• Active liver disease
• Thromboembolic disorders

Common side effects

• Headache
• Breast pain
• Nausea
• Dizziness
• Application site reactions

Counselling Points

• Apply to clean, dry skin
• Change patch every 3-4 days
• Report any unusual bleeding
• Avoid use during pregnancy