Flucoric 50 mg, 100 mg, 150 mg, 200 mg Capsule
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various fungal infections including cryptococcal meningitis and candidiasis.
Dosage (summary)
400 mg on day 1, then 200 mg daily for cryptococcal meningitis; 50-400 mg daily for candidiasis.
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; present in breast milk, not recommended during breastfeeding.
Key Drug Interactions
- Terfenadine
- Cisapride
- Erythromycin
- Pimozide
- Quinidine
Contraindications
- Hypersensitivity to fluconazole
- Co-administration with terfenadine at high doses
Common side effects
- Headache
- Nausea
- Abdominal pain
- Rash
- QT prolongation
Counselling Points
- Monitor for liver function
- Avoid in pregnancy
- Use effective contraception during treatment
Serious warnings
- Hepatotoxicity
- QT prolongation
- Serious skin reactions
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